Practice all 11 Pathology MCQs from previous BCS Preliminary exams.
Bony metastasis may occur in-
Follicular thyroid carcinoma spreads characteristically via the bloodstream (hematogenous spread), commonly causing osteolytic bone metastases.
The antigen presenting cell on skin is
Langerhans cells are specialized dendritic antigen-presenting cells residing in the stratum spinosum of the epidermis.
Causative Organism responsible for Cervical cancer
High-risk Human Papillomavirus (HPV types 16 and 18) integration into host DNA causes over 90% of invasive cervical cancers.
Leukocyte induced acute tissue injury is-
Neutrophilic and leukocytic infiltration with release of lysosomal enzymes directly mediates acute joint tissue injury in acute arthritis.
In acute inflammation, pain occurs due to -
Pain in acute inflammation is mediated by chemical mediators such as bradykinin, prostaglandins (PGE2), and histamine which sensitize sensory nerve endings.
Bence-Jones proteins are
Bence Jones proteins are free monoclonal immunoglobulin light chains (kappa or lambda) excreted in the urine of patients with multiple myeloma.
Following infections are common in immunodeficient patient except
Opportunistic infections (Pneumocystis jirovecii, CMV, Candida) are hallmark infections in immunodeficient hosts, while Corynebacterium diphtheriae is a vaccine-preventable toxin-mediated infection.
Commonest tumors of the central nervous system arise from
Gliomas (astrocytomas, glioblastomas arising from neuroglial cells) and meningiomas (arising from arachnoid cap cells of the meninges) account for the vast majority of primary intracranial tumors.
Features of CSF in pyogenic meningitis
CSF analysis in acute pyogenic meningitis demonstrates marked polymorphonuclear pleocytosis, markedly elevated protein, and very low glucose/CSF-to-plasma glucose ratio.
Biochemical disturbance occurs in fulminating hepatic failure is
Acute liver failure is clinically defined by severe coagulopathy (prolongation of prothrombin time / INR ≥ 1.5) and hepatic encephalopathy within 8–24 weeks.
Coombs' test is used for detecting
The direct and indirect antiglobulin (Coombs') tests detect autoimmune hemolytic antibodies, such as warm IgG and cold IgM agglutinins binding to RBCs.
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